Check-up «Kidney Function Test»

Basic laboratory examination to assess kidney function, mineral metabolism and protein levels in the blood. This includes eight indicators: urea, creatinine, uric acid, calcium, phosphorus, total protein, albumin and globulins.

Analysis Description

The kidneys are responsible for the excretion of metabolic products, regulation of acid-base balance, pressure and fluid levels in the body. Renal dysfunction can proceed for a long time without symptoms, but lead to serious consequences − from edema to anemia and cardiovascular complications. The analysis allows you to identify early signs of filtration disorders, metabolite retention, protein deficiency and mineral imbalance. Suitable for basic monitoring of kidney function, especially in the presence of chronic diseases or taking nephrotoxic drugs.

The lab diagnostics detect

Assessment of renal function when complaining of edema, weakness, urinary dysfunction

Screening for arterial hypertension and diabetes mellitus

Monitoring the condition when taking nephrotoxic drugs

Diagnosis of mineral disorders (calcium, phosphorus)

Suspected chronic kidney disease (CKD)

Routine assessment of renal function before surgery or initiation of therapy

Indications

Suspected chronic kidney disease

Edema, high blood pressure, changes in urine

Arterial hypertension, diabetes mellitus

Monitoring when taking nephrotoxic drugs

Diagnosis of protein and mineral metabolism disorders

Preparation for surgery, chemotherapy, initiation of systemic therapy

Analysis Composition and Interpretation

Urea

The end product of protein metabolism, excreted by the kidneys. It is a sensitive indicator of nitrogen metabolism and renal excretory function. Changes in urea levels help to identify filtration disorders or increased protein catabolism.

Normal range: 2.5–8.3 mmol/l

Reasons for increased values: chronic and acute renal failure, dehydration, gastrointestinal bleeding, increased catabolism
Reasons for decreased values: liver diseases, insufficient protein intake with food, hyperhydration, pregnancy

Creatinine

A product of muscle creatine metabolism. The indicator most resistant to external factors. Used to calculate the glomerular filtration rate and determine the degree of renal failure.

Normal range:

Men: 62–115 µmol/l
Women: 53–97 µmol/l

Reasons for increased values: renal failure, urinary tract obstruction, intake of nephrotoxic drugs, significant physical activity
Reasons for decreased values: decreased muscle mass, exhaustion, pregnancy, liver disease

Uric Acid

Formed during the breakdown of purines and excreted by the kidneys. Increased levels may indicate excretion disorders or increased cellular breakdown. Used in the diagnosis of gout and monitoring of kidney function.

Normal range:

Men: 210–420 µmol/l
Women: 150–350 µmol/l

Reasons for increased values: gout, chronic kidney disease, high cell death (in cancer processes), diet with excess purines
Reasons for decreased values: liver diseases, taking uricosuric drugs, Fanconi syndrome

Calcium

A mineral necessary for muscle function, the nervous system and blood clotting. Renal function affects the level of free calcium. Imbalances in levels may be associated with changes in vitamin D metabolism and parathyroid gland function.

Normal range: 2.15–2.65 mmol/l

Reasons for increased values: hyperparathyroidism, malignant neoplasms, excess vitamin D, immobilization
Reasons for decreased values: chronic renal failure, hypoparathyroidism, vitamin D deficiency, impaired calcium absorption

Phosphorus

A mineral involved in energy metabolism (ATP), bone tissue construction and acid-base balance. Excreted through the kidneys. Phosphate levels help assess the mineral balance in CKD and bone metabolism disorders.

Normal range: 0.81–1.45 mmol/l

Reasons for increased values: CKD, hypoparathyroidism, acidosis, excess phosphate intake
Reasons for decreased values: hyperparathyroidism, vitamin D deficiency, malabsorption, chronic starvation

Total Protein

The sum of all serum proteins − albumin and globulins. Used to assess overall protein metabolism and may change with protein loss in the urine, nutritional disorders or protein synthesis.

Normal range: 64–83 g/l

Reasons for increased values: dehydration, chronic inflammation, multiple myeloma
Reasons for decreased values: nephrotic syndrome, liver cirrhosis, insufficient protein intake, gastrointestinal diseases

Albumin

The main plasma protein, synthesized in the liver. The level decreases with protein loss in the urine, synthesis disorders or inflammatory processes. Important for assessing protein loss in nephrotic syndrome. Normal range: 35–50 g/l

Reasons for increased values: dehydration
Reasons for decreased values: loss of protein in the urine (nephrotic syndrome), liver disease, inflammatory processes, malnutrition

Globulin

A group of proteins including immunoglobulins and acute phase proteins. It is determined by calculation as the difference between total protein and albumin. Helps in assessing immune activity and inflammatory processes.

Normal range: 20–35 g/l (approximately)

Reasons for increased values: chronic inflammation, autoimmune diseases, infections
Reasons for decreased values: hypogammaglobulinemia, immunodeficiencies, exhaustion

Check-up «Kidney Function Test»

290 AED

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