Check-up «Coagulation Test»

Laboratory study of the blood coagulation system. Includes complete blood count, prothrombin time (PT/INR), activated partial thromboplastin time (APTT/PTT) and fibrinogen level.

Analysis Description

Blood clotting is a complex physiological process that ensures the cessation of bleeding when blood vessels are damaged. Disturbances in the hemostasis system can lead to thrombosis or, conversely, to increased bleeding. This check-up allows you to comprehensively assess the main parameters of primary and plasma hemostasis. Used in preparation for surgery, to monitor anticoagulant therapy, and when coagulopathy is suspected.

The lab diagnostics detect

Screening for blood clotting disorders

Preparation for surgical interventions and invasive procedures

Monitoring anticoagulant therapy

Diagnosis of bleeding, bruising, nosebleeds and uterine bleeding

Monitoring for liver disease, autoimmune and oncological conditions

Indications

Preparation for surgical interventions and invasive procedures

Bleeding gums, nosebleeds, heavy menstruation, frequent hematomas

Long-term wound healing, bruises without cause

Taking anticoagulants (warfarin, heparin)

Diagnosis of liver diseases

Suspected thrombophilia or coagulopathy

Monitoring during pregnancy or cancer

Analysis Composition and Interpretation

Complete Blood Count (CBC with Erythrocyte)

Shows the number and ratio of formed elements of the blood (erythrocytes, leukocytes, platelets), hemoglobin level, hematocrit, color index, etc.

Erythrocytes
Red blood cells carry oxygen from the lungs to the tissues and carbon dioxide back. Contain hemoglobin and are responsible for gas exchange.
Normal range:

Men: 4.5–5.5 × 10¹²/l
Women: 3.8–4.8 × 10¹²/l

Reasons for increased values (erythrocytosis): dehydration, chronic hypoxia, lung diseases, congenital heart defects, erythremia.
Reasons for decreased values (erythrocytosis): anemia, blood loss, chronic inflammatory diseases, bone marrow hematopoiesis disorders.

Hemoglobin
Protein contained in red blood cells. Provides transport of oxygen and carbon dioxide. Is the main indicator of the oxygen capacity of the blood.
Normal range:

Men: 130–160 g/l
Women: 120–150 g/l

Reasons for increased values: thickening of blood due to dehydration, chronic hypoxia, erythrocytosis, lung diseases, smoking.
Reasons for decreased values: anemia (iron deficiency, B12 deficiency, chronic), blood loss, pregnancy.

Leukocytes
White blood cells, perform a protective function. Participate in immune reactions, destroy infectious agents and atypical cells.

Normal range: 4.0–9.0 × 10⁹/l

Reasons for increased values (leukocytosis): bacterial infections, inflammation, trauma, malignant neoplasms, leukemia, glucocorticoid intake.
Reasons for decreased values (leukocytosis): viral infections, bone marrow suppression, aplastic anemia, autoimmune diseases, cytostatics.

Platelets
Cells involved in blood clotting. Provide primary hemostasis − form a platelet plug at the site of vascular damage.

Normal range: 150–400 × 10⁹/l

Reasons for increased values (thrombocytosis): inflammatory processes, iron deficiency anemia, after removal of the spleen, myeloproliferative diseases.
Reasons for decreased values (thrombocytosis): viral infections, autoimmune conditions, taking certain medications, liver cirrhosis, thrombocytopenic purpura, leukemia.

Prothrombin Time (PT) and International Normalized Ratio (INR)

Assesses the external coagulation pathway. INR allows standardization of PT results between different laboratories. Used to monitor warfarin therapy and assess liver function.

Normal range of PT: 11–15 seconds
Normal range of INR: 0.8–1.2 (in the absence of therapy)

Reasons for increased values: deficiency of coagulation factors, taking anticoagulants (warfarin), liver disease, vitamin K deficiency
Reasons for decreased values: hypercoagulation, thrombosis, increased coagulation factors

Activated Partial Thromboplastin Time (APTT)

Reflects the activity of the intrinsic coagulation pathway. Used to diagnose hereditary coagulopathies and monitor heparin therapy.

Normal range of APTT: 25–35 seconds

Reasons for increased values: hemophilia, deficiency of factors VIII, IX, XI, von Willebrand disease, heparin therapy
Reasons for decreased values: hypercoagulation, inflammatory conditions, pregnancy

Fibrinogen

One of the key proteins involved in the formation of a fibrin clot. It is a marker of acute inflammation and is used to assess the risk of thrombosis.

Normal range: 1.8–4.0 g/l

Reasons for increased values: acute inflammations, infections, burns, pregnancy, malignant tumors
Reasons for decreased values: DIC-syndrome, severe liver damage, coagulopathy, hereditary deficiency

Check-up «Coagulation Test»

300 AED