Check-up «Liver Function Test» at Refresh Clinic Dubai

Check-up «Liver Function Test»

The liver is involved in metabolism, the synthesis of proteins, enzymes and hormones, as well as in detoxification. Disorders of its function may be asymptomatic. The check-up allows you to assess the degree of inflammation, signs of cholestasis, impaired protein-synthetic function and possible systemic changes. It is used in the diagnosis of liver and biliary tract diseases, monitoring therapy and in planned preparation for treatment.

Diagnosis of acute and chronic liver diseases

Monitoring of liver function when taking hepatotoxic drugs

Detection of bile outflow disorders

Assessment of suspected fatty liver disease, hepatitis, cirrhosis

Screening before surgery or chemotherapy

Complaints of heaviness in the right hypochondrium, nausea, bitterness in the mouth

Increased liver enzymes in previous tests

Suspected hepatitis, fatty liver disease, cirrhosis

Monitoring therapy when taking potentially hepatotoxic drugs

Screening before surgery, chemotherapy or long-term medication

Chronic alcohol consumption

Programme components

Total Bilirubin

A chemical compound that is formed during the breakdown of hemoglobin. Consists of direct and indirect fractions. It is used to assess jaundice and hepatobiliary diseases.

Include

Normal range: 3–21 µmol/l

Indicators above normal: viral hepatitis, cirrhosis, Gilbert's syndrome, hemolysis, mechanical jaundice
Indicators below normal: no diagnostic value

Direct Bilirubin

Fraction of bilirubin bound in the liver with glucuronic acid. This form is water-soluble and excreted in bile.

Include

Normal range: 0–5 µmol/l

Indicators above normal: cholestasis, liver tumors, hepatitis, biliary obstruction
Indicators below normal: no diagnostic value

Indirect Bilirubin

Fraction not bound in the liver. Formed during the breakdown of red blood cells.

Include

Normal range: up to 16 µmol/l

Indicators above normal: hemolytic anemia, Gilbert's syndrome, neonatal jaundice
Indicators below normal: no diagnostic value

Alanine aminotransferase (ALT/SGPT)

An enzyme primarily localized in liver cells. The level increases with damage to liver cells. Used to diagnose viral and toxic hepatitis, fatty hepatosis and drug reactions.

Include

Normal range: up to 40 U/l

Indicators above normal: acute or chronic hepatitis, fatty liver disease, toxic damage
Indicators below normal: possible with severe liver failure, decreased muscle mass

Aspartate aminotransferase (AST/SGOT)

Present in the liver, cardiac muscle and skeletal muscles. AST levels are assessed together with ALT to determine the source of cellular damage. The AST/ALT ratio helps to clarify the nature of the disease and suspect cirrhosis.

Include

Normal range: up to 40 U/l

Indicators above normal: viral hepatitis, cirrhosis, myocardial infarction, alcoholic liver disease
Indicators below normal: rare, can be observed in muscular dystrophy

Alkaline phosphatase (ALP)

An enzyme whose level increases when bile outflow is impaired. Also produced in bone tissue. Together with GGT, it helps to identify intrahepatic or extrahepatic obstruction.

Include

Normal range: 40–150 U/l

Indicators above normal: cholestasis, liver tumors, biliary obstruction, bone diseases
Indicators below normal: hypophosphatemia, hypothyroidism, zinc deficiency

Gamma Glutamyl Transferase (GGT)

An enzyme involved in amino acid metabolism. It is a sensitive marker of cholestasis and toxic liver damage. An increase in levels is often observed with alcohol abuse and long-term medication use.

Include

Normal range:

Men: up to 60 U/l
Women: up to 40 U/l

Indicators above normal: alcoholism, medication, cholestasis, liver tumors
Indicators below normal: no clinic value

Total Protein

The sum of all protein fractions in the blood serum. The level reflects the synthetic function of the liver and the general state of protein metabolism.

Include

Normal range: 64–83 g/l

Reasons for increased values: chronic inflammatory diseases, infections, myeloma
Reasons for decreased values: cirrhosis, nephrotic syndrome, exhaustion, malabsorption

Albumin

The main plasma protein, synthesized in the liver. Maintains oncotic pressure, participates in the transportation of hormones, bilirubin and drugs.

Include

Normal range: 35–50 g/l

Reasons for increased values: dehydration
Reasons for decreased values: liver failure, chronic inflammation, nephrotic syndrome

Albumin/Globulin Ratio (A/G Ratio)

A coefficient characterizing the relative content of albumin and globulins.

Include

Normal range: 1.2–2.2

Reasons for increased values: possible with dehydration
Reasons for decreased values: chronic liver diseases, autoimmune processes, infections

Check-up «Liver Function Test»

370 AED

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Check-up «Liver Function Test»

Check-up «Liver Function Test»

Key Advantagesof Refresh Clinic

Key Advantages
of Refresh Clinic