Peptide Melanotan 2 (MT-II) is a synthetic cyclic analogue of alpha-melanocyte-stimulating hormone (α-MSH). It acts as a non-selective agonist of melanocortin receptors MC1R-MC5R, which allows it to influence various ...

Peptide Melanotan 2 (MT-II) is a synthetic cyclic analogue of alpha-melanocyte-stimulating hormone (α-MSH). It acts as a non-selective agonist of melanocortin receptors MC1R-MC5R, which allows it to influence various physiological processes in the body.

Main effects of Melanotan 2:

  1. Pigmentation: MT-II stimulates melanin production, leading to enhanced tanning and improved skin color. This makes it popular among people seeking a darker skin tone without prolonged sun exposure.

  2. Libido: The peptide is also known for its positive effect on sexual desire. It can increase testosterone levels and improve sexual function in men and women.

  3. Metabolism: MT-II promotes appetite suppression and increased energy expenditure, which may help with weight loss and improving overall health.

Effect

Mechanism

Speed

Duration

Tan

↑Melanogenesis

3-7 days

2-4 months

Libido

MC4R activation

1-3 hours

6-12 hours

Appetite

↓Hypothalamic hunger

2-4 days

1-2 weeks

Fat burning

↑Thermogenesis

7-14 days

Course-based

Melanotan 2 popularity in 2026

#3 aesthetic peptide after PT-141:

- 92% satisfaction with tan

- 78% note ↑libido

Stack

Advantages

Dose MT-II + partner

Frequency

1. MT-II + PT-141

Tan + libido x3 (MC4R)

250 mcg + 1 mg s/c

3-5 times/week

2. MT-II + GHK-Cu

Tan + collagen/skin regen

250 mcg + 1 mg

Daily

3. MT-II + CJC-1295/Ipamorelin

Tan + GH/fat burning

250 mcg + 100/100 mcg

5 times/week

4. MT-II + BPC-157

Tan + tissue regen

250 mcg + 250 mcg

5 times/week

5. MT-II + Kisspeptin

Tan + testosterone/libido

250 mcg + 200 mcg

3 times/week

6. MT-II + Tirzepatide

Tan + appetite x2

250 mcg + 5 mg/week

5 times/week

Like any other medication, Melanotan 2 can cause side effects such as nausea, headache, skin flushing, and elevated blood pressure. Before starting use, it is recommended to consult a doctor and undergo a medical examination.

Melanotan II / Melanotan 2 is a powerful peptide that can have a significant impact on various aspects of health and appearance. Its use should be cautious and under specialist supervision to ensure maximum benefit and minimize risks.

Information

Information about peptides is provided for informational and reference purposes only. The peptides presented are for research and laboratory use only and are not intended for human or veterinary use or consumption. The information on this website does not constitute medical advice, a prescription, or instructions for use and is not intended for the diagnosis, treatment, or prevention of any disease. Peptides displayed in the catalogue are not offered for sale through this website. A consultation does not constitute a means of ordering, purchasing, or obtaining any products displayed. Images are for illustrative purposes only.