Nicotinamide adenine dinucleotide (NAD+) is a coenzyme that serves as the central link in cellular energy metabolism. It is involved in oxidation-reduction processes, ensuring stable mitochondrial function and supporting cell-level metabolism.
By the age of fifty, NAD+ concentration decreases by half, which is directly linked to impaired mitochondrial function and the development of pathologies associated with aging. This substance is a critically important cofactor for maintaining health and increasing life expectancy.
|
Release Format |
Dosage |
Absorption |
|---|---|---|
|
Intravenous (infusion) |
250–1000 mg per procedure |
Complete (100%) |
|
Oral (NMN/NR) |
500–1000 mg daily |
30–50% |
|
Sublingual |
100–300 mg |
70–90% |
Applications of NAD+
-
Neurocognitive support: optimizes memory processes, attention focus, and overall brain activity.
-
Immune response: strengthens body defenses, increasing resistance to infections and reducing the intensity of inflammatory reactions.
-
Anti-aging effect: involved in DNA repair mechanisms and inhibits cellular senescence.
-
Energy potential: accelerates intracellular energy production, which is indispensable during intense physical or psycho-emotional stress. Provides support to the cardiovascular system.
|
Sphere of Influence |
Results |
|---|---|
|
Vitality |
Mitochondrial activation↑, fighting asthenia |
|
Anti-aging |
SIRT1 stimulation↑, synergy with Epithalon for telomeres |
|
Metabolism |
Insulin regulation↑, correction of NAFLD and excess weight |
|
Neurology |
Improvement of cognitive indicators, prevention of Alzheimer's disease |
Current 2026 Ranking
#2 in the anti-aging peptides category (after NMN):
-
Precursors NMN/NR
-
Injector pens and NAD+ infusions
-
MOTS-c (mitochondrial function)
-
Epithalon (telomere protection)
Methods for Increasing NAD+ Concentration
This coenzyme can be replenished through several pathways:
-
Dietary adjustment: inclusion of foods high in B vitamins (organ meats, fish, nuts, seeds).
-
Physical exercise: systematic training stimulates NAD+ synthesis and improves general well-being.
-
Supplements: intake of precursors such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN).
|
Combination (Stack) |
Purpose |
Proportions |
|---|---|---|
|
NAD+ + Epitalon |
DNA and telomere repair |
500 mg IV + 5 mg |
|
NAD+ + ARA-290 |
Neuropathy and energy supply |
500 mg + 2 mg |
|
NAD+ + Glow |
Dermatological effect and mitochondria |
500 mg + 0.15 ml |
|
NAD+ + PE-22-28 |
Anti-stress and cognition |
500 mg + 200 mcg |
Nicotinamide adenine dinucleotide is not just an auxiliary enzyme, but a fundamental tool for managing biological age. In 2026, it solidifies its status as the standard of anti-aging medicine, proving its effectiveness in matters of metabolic maintenance, energy status, and central nervous system function. Maintaining a high concentration of NAD+ contributes to improving quality of life and slowing down biological clocks.
Recommended Therapy Protocols
|
Course Stage |
Dose Volume |
Frequency |
Administration Time |
|---|---|---|---|
|
Adaptation (Loading) |
250–500 mg |
2–3 times a week |
2–4 hours (slow infusion) |
|
Stabilization (Maintenance) |
250–500 mg |
Once a week or once a month |
1–2 hours |
|
Maximum Longevity |
500–1000 mg |
8–15 sessions per year |
Interval of 3–7 days |
For chronic fatigue:
Infusion therapy of NAD+ at 500 mg twice a week (course of 10 procedures) combined with daily oral intake of NR at a dosage of 500 mg.
Important: prior to using these protocols, consultation with a specialist is mandatory to identify contraindications and guarantee the safety of the ongoing therapy.
Availability in Dubai: Nicotinamide adenine dinucleotide (NAD+) is available in the form of intravenous systems, auto-injectors (pens), nasal sprays, and transdermal patches.
Information
Smart Benefits.
Maximum Impact.
The Science of Longevity in Detail
