SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that interacts with cardiolipin in the inner mitochondrial membrane. It is being studied for its potential role in supporting mitochondrial function, cellular energy metabolism, and protection against oxidative stress. Research is exploring its potential applications in cardiovascular and neurological health, as well as age-related cellular changes.
Synonyms: Elamipretide, MTP-131, Bendavia, SS-31
Molecular formula: C₃₂H₄₉N₉O₅
SS-31 (Elamipretide) is a synthetic mitochondria-targeted tetrapeptide developed to act on the inner mitochondrial membrane. It interacts with cardiolipin, a structural component of the mitochondrial me...
SS-31 (Elamipretide) is a synthetic mitochondria-targeted tetrapeptide developed to act on the inner mitochondrial membrane. It interacts with cardiolipin, a structural component of the mitochondrial membrane, and is being investigated in the context of supporting mitochondrial function, cellular energy metabolism, and oxidative stress regulation.
Elamipretide selectively accumulates in mitochondria and binds to cardiolipin. Through this interaction, it is being investigated for its potential role in maintaining mitochondrial membrane integrity and processes involved in cellular energy production. Another area of research focuses on its effects on oxidative stress and mitochondrial dysfunction.
Elamipretide is being studied in areas related to impaired mitochondrial function. Research primarily focuses on its interaction with mitochondrial membranes, cardiolipin, and related cellular metabolic processes. Clinical evidence for specific conditions continues to evolve, so the use of SS-31 beyond approved indications should be considered investigational.
